DescriptionWhat was the hydrocortisone tapering protocol in the Annane 2002 trial? Did tranexamic acid increase VTE rates in the CRASH 2 trial? Which type of bacterial meningitis showed benefit with dexamethasone?
Critical care encompasses a wide array of disease states with ever-changing, conflicting literature. As clinicians, it is important to be knowledgeable of seminal landmark trials, but also be familiar with the most cutting-edge pivotal trials.
ICU Trials by ClinCalc is a quick pocket reference for both the novice and seasoned ICU clinician. This app does not replace the original manuscript of these landmark trials – instead, it serves as a fast reference and learning tool for some of the most important critical care trials over a wide range of specialties.
Each trial contains a short one-liner about the trial and key points, which includes only the most pertinent details, such as inclusion/exclusion criteria, treatment protocols, pertinent endpoints and findings, as well as expert commentary regarding key subgroup analyses or limitations to the trial.
Each trial contains a “Send to Colleague” button, which allows you to send the PubMed citation and link to a colleague. Using this feature, it’s incredibly easy to share pivotal trials with students, residents, and other colleagues.
The database features 50+ landmark trials related to: ARDS, cardiac arrest, DVT/PE, delirium, glycemic control, heart failure, hemorrhage, meningitis, nephroprotection, nutrition, pneumonia, sedation, seizure, sepsis/shock, spinal cord injury, stroke, and subarachnoid hemorrhage – with more trials and topics to be added on a regular basis!
This app is designed and maintained by Sean P. Kane, PharmD, BCPS -- a clinical pharmacist specializing in critical care with a background in information technology and application development.