Install a Camera Launcher
The Nexus 7 has a front-facing camera but there's no way to launch it from the homescreen out of the box. Install Camera Launcher by MoDaCo to be able to launch the device's camera straight from the homescreen.
Install Adobe Flash
Apple's iOS doesn't support Flash, but your brand new device does. While the Flash app is long gone from Google Play, you can still install it by downloading the APK from XDA developers (make sure to go to settings –> security first and check "unknown sources.")
Unlock Screen Rotation
A funny thing happened when Eric brought the Nexus 7 to AndroidPIT's offices for the first time: we couldn't initially figure out how to rotate the screen to landscape mode. Eric joked, "I feel like I just bought a giant phone." In fact, you can unlock screen rotation. Just pul down the notifcation bar and click the lock next to "Settings."
Transform Your Nexus 7 Into a Kindle eReader
Seriously, who needs a Kindle when you can download Amazon's Kindle app and sync your e-books to your Nexus 7? It's got by far the greatest number of books of any ereader app.
Play VLC Video Files